{"id":311,"date":"2011-04-13T10:55:37","date_gmt":"2011-04-13T01:55:37","guid":{"rendered":"http:\/\/ft-net.co.jp\/topic\/?p=311"},"modified":"2013-11-12T15:51:02","modified_gmt":"2013-11-12T06:51:02","slug":"%e3%80%8c18f%e6%94%be%e5%b0%84%e6%80%a7%e3%83%88%e3%83%ac%e3%83%bc%e3%82%b5%e3%83%bc%e3%80%8d","status":"publish","type":"post","link":"https:\/\/ft-net.co.jp\/topic\/?p=311","title":{"rendered":"\u300c18F\u653e\u5c04\u6027\u30c8\u30ec\u30fc\u30b5\u30fc\u300d"},"content":{"rendered":"

\u6700\u65b0\u30d5\u30c3\u7d20\u95a2\u9023\u30c8\u30d4\u30c3\u30af\u30b9\u300d\u306f\u30c0\u30a4\u30ad\u30f3\u5de5\u696d\u682a\u5f0f\u4f1a\u793e\u30d5\u30a1\u30a4\u30f3\u30b1\u30df\u30ab\u30eb\u90e8\u306e\u3054\u597d\u610f\u306b\u3088\u308a\u3001\u30c0\u30a4\u30ad\u30f3\u5de5\u696d\u30db\u30fc\u30e0\u30da\u30fc\u30b8\u306eWEB\u30de\u30ac\u30b8\u30f3\u306b\u63b2\u8f09\u3055\u308c\u305f\u5185\u5bb9\u3092\u7d39\u4ecb\u3057\u3066\u3044\u307e\u3059\u3002\u3054\u611b\u9867\u306e\u307b\u3069\u3088\u308d\u3057\u304f\u304a\u9858\u3044\u3044\u305f\u3057\u307e\u3059\u3002\u5c1a\u3001WEB\u30de\u30ac\u30b8\u30f3\u306eURL\u306f\u4e0b\u8a18\u306e\u901a\u308a\u3067\u3059\u3002http:\/\/www.daikin.co.jp\/chm\/products\/fine\/backnum\/201103\/#topic01<\/p>\n

1\u3001\u306f\u3058\u3081\u306b
\n18F\u306f\u3001\u305d\u306e\u4f4e\u3044\u967d\u96fb\u5b50\u653e\u51fa\u30a8\u30cd\u30eb\u30ae\u30fc\u3001\u30b5\u30a4\u30c9\u30a8\u30df\u30c3\u30b7\u30e7\u30f3\u304c\u306a\u3044\u3053\u3068\u3001\u304a\u3088\u3073\u9069\u5207\u306a\u534a\u6e1b\u671f\u306e\u305f\u3081\u306b\u3001\u6700\u3082\u5e83\u304f\u4f7f\u7528\u3055\u308c\u3066\u3044\u308bPET(\u967d\u96fb\u5b50\u691c\u51fa\u3092\u5229\u7528\u3057\u305f\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u30fc\u65ad\u5c64\u64ae\u5f71\u6280\u8853)\u540c\u4f4d\u4f53\u306e\uff11\u3064\u3067\u300118F\u3092\u542b\u3093\u306018F\uff0d\u30d5\u30eb\u30aa\u30ed\uff0d\u30c7\u30aa\u30ad\u30b7\uff0d\u30b0\u30eb\u30b3\u30fc\u30b9(18F-FDG)\u306a\u3069\u306e\u653e\u5c04\u6027\u30c8\u30ec\u30fc\u30b5\u30fc\u304c\u7a2e\u3005\u958b\u767a\u3055\u308c\u3066\u3044\u308b\u3002PET\u30b7\u30b9\u30c6\u30e0\u306b\u3088\u308b\u753b\u50cf\u8a3a\u65ad\u6cd5\u306f\u3001\u764c\u8a3a\u65ad\u3042\u308b\u3044\u306f\u8133\u6a5f\u80fd\u8a3a\u65ad\u306b\u6709\u7528\u3067\u3042\u308b\u3002
\n\u3053\u3053\u3067\u306f\u3001\u6700\u65b0\u306e\u7279\u8a31\u30fb\u6587\u732e\u304b\u308918F\u653e\u5c04\u6027\u30c8\u30ec\u30fc\u30b5\u30fc\u306b\u3064\u3044\u3066\u307e\u3068\u3081\u3066\u307f\u305f\u3002<\/p>\n

2\u3001\u30a2\u30df\u30ce\u9178\u30d9\u30fc\u30b9\u306e\u30c8\u30ec\u30fc\u30b5\u30fc
\n\u30a2\u30df\u30ce\u9178\u30d9\u30fc\u30b9\u306e\u30c8\u30ec\u30fc\u30b5\u30fc\u306f\u816b\u760d\u4ee3\u8b1d\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5264\u3068\u3057\u3066\u81e8\u5e8a\u9069\u7528\u306b\u6709\u7528\u3067\u3042\u308b\u3002Hank F. Kung \u3089\u306f\u3001\u4e0b\u8a18\u306e\u4e8c\u3064\u306e\u65b0\u3057\u3044\u30d5\u30a7\u30cb\u30eb\u30a2\u30e9\u30cb\u30f3\u8a98\u5c0e\u4f53FEP\u3068FPP\u3092\u5408\u6210\u3057\u3001\u73fe\u5728\u81e8\u5e8a\u306b\u4f7f\u308f\u308c\u3066\u3044\u308bFET\u3068\u6bd4\u8f03\u3057\u3066\u3044\u308b\u30021)
\n\"FT1\"
\nFEP\u3068FPP\u306e\u5408\u6210\u306f\u4e0b\u8a18\u306e\u3088\u3046\u306b\u884c\u3063\u305f\u3002\u53ce\u7387\u306f11\uff5e37%\u3001\u93e1\u50cf\u7570\u6027\u7d14\u5ea690%\u3001\u6bd4\u653e\u5c04\u80fd\u306f21\uff5e69GBq\/\u03bcg\u3067\u3042\u3063\u305f\u3002
\n\"FT2\"
\n\u7d30\u80de\u6442\u53d6\u306b\u3064\u3044\u3066\u306f\u3001\u4e0b\u56f3\u306b\u793a\u3059\u3088\u3046\u306bFEP\u304c\u9ad8\u3044\u5024\u3092\u793a\u3057\u305f\u3002\u305d\u3057\u3066\u3001\u30cd\u30ba\u30df\u3092\u4f7f\u3063\u3066\u306e\u751f\u4f53\u5185\u8a55\u4fa1\u3067\u306f\u3001\u6709\u7528\u306a\u30c8\u30ec\u30fc\u30b5\u30fc\u3067\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u305f\u3002
\n\"FT3\"
\n\u307e\u305f\u30012-[18F]fluoro-L-phenylalanine\u306f\u4eba\u9593\u306e\u751f\u4f53\u5185\u8840\u6db2\u8133\u95a2\u9580\u3067\u306e\u4e2d\u6027\u30a2\u30df\u30ce\u9178\u904b\u642c\u306e\u7814\u7a76\u306b\u304a\u3051\u308b\u6709\u7528\u306a\u653e\u5c04\u6027\u533b\u85ac\u3067\u3042\u308b\u3002\u4ed6\u65b9\u30012-[18F]fluoro-L-tyrosine\u306f\u4ed6\u306e\u30cf\u30ed\u30b2\u30f3\u5316\u30a2\u30df\u30ce\u9178\u3068\u7570\u306a\u308a\u3001\u6b86\u3069\u5b9a\u91cf\u7684\u306b\u305f\u3093\u767d\u8cea\u306b\u53d6\u308a\u8fbc\u307e\u308c\u3001\u751f\u4f53\u5185\u30bf\u30f3\u30d1\u30af\u8cea\u5408\u6210\u306e\u9020\u5f71\u306b\u5bfe\u3059\u308b\u30c8\u30ec\u30fc\u30b5\u30fc\u3068\u3057\u3066\u6709\u7528\u3067\u3042\u308b\u3002\u3044\u305a\u308c\u3082\u6b63\u5e38\u306e\u7d44\u7e54\u3068\u816b\u760d\u3068\u3092\u533a\u5225\u3059\u308b\u3053\u3068\u304c\u51fa\u6765\u308b\u306e\u3067\u3001\u305d\u308c\u3089\u306e\u6442\u53d6\u306ePET\u7814\u7a76\u306f\u8133\u816b\u760d\u306e\u75c5\u6027\u9451\u5b9a\u306b\u5bfe\u3059\u308b\u81e8\u5e8a\u4fa1\u5024\u304c\u3042\u308b\u3002\u3053\u308c\u3089\u306e\u5408\u6210\u6cd5\u306f\u3001\u3044\u305a\u308c\u3082[18F]F2\u3001[18F]AcOF\u3092\u7528\u3044\u3066\u3001L-phenylalanine\u3084L-tyrosine\u306e\u76f4\u63a5\u30d5\u30c3\u7d20\u5316\u306b\u3088\u308a\u5408\u6210\u3055\u308c\u3066\u304d\u305f\u304c\u3001\u53ce\u7387\u304c\u4f4e\u3044\u306a\u3069\u306e\u554f\u984c\u70b9\u304c\u3042\u3063\u305f\u3002Johannes Ermert\u3089\u306f\u3001\u4e0b\u8a18\u306b\u793a\u3059\u3088\u3046\u306a\u3053\u308c\u3089\u306e\u30a8\u30ca\u30f3\u30c1\u30aa\u7279\u7570\u7684\u306a\u65b0\u898f\u5408\u6210\u6cd5\u3092\u958b\u767a\u3057\u305f\u30022)\u3064\u307e\u308a\u3001\u51fa\u767a\u7269\u8cea\u306b\u4e0b\u8a18\u306b\u793a\u30591a\u30011b\u3092\u7528\u3044\u3066\u3001\u540c\u4f4d\u4f53\u5909\u63db\u3092\u884c\u3044\u3001Rh(PPh3)3Cl\u306b\u3088\u308a\u8131\u30ab\u30eb\u30dc\u30cb\u30eb\u5316\u53cd\u5fdc\u3092\u884c\u3044\u3001\u6700\u5f8c\u306b\u52a0\u6c34\u5206\u89e3\u3057\u3066\u30a2\u30df\u30ce\u9178\u3092\u5f97\u308b\u3068\u3044\u30463\u6bb5\u968e\u6cd5\u3067\u3042\u308b\u3002\u53ce\u7387\u306f\u305d\u308c\u305e\u308c43%\u306849%\u3001\u30a8\u30ca\u30f3\u30c1\u30aa\u30de\u30fc\u7d14\u5ea6\u306f94%\u3068\u9ad8\u304f\u3001PET\u306b\u3088\u308b\u81e8\u5e8a\u8a66\u9a13\u306b\u5341\u5206\u6709\u52b9\u3067\u3042\u3063\u305f\u3002
\n\"FT4\"
\n3\u3001\u30b3\u30ea\u30f3\u7cfb\u30c8\u30ec\u30fc\u30b5\u30fc
\n\u30b3\u30ea\u30f3\u653e\u5c04\u6027\u30c8\u30ec\u30fc\u30b5\u30fc\u306f\u816b\u760d\u5b66\u306b\u304a\u3051\u308b\u81e8\u5e8aPET\u8a3a\u65ad\u306b\u5e83\u304f\u7528\u3044\u3089\u308c\u3066\u3044\u308b\u30022-[18F]-2-\u30c7\u30aa\u30ad\u30b7-D-\u30b0\u30eb\u30b3\u30fc\u30b9\u306f\u9ad8\u3044\u30d0\u30c3\u30af\u30b0\u30e9\u30f3\u30c9\u306e\u53d6\u308a\u8fbc\u307f\u3092\u793a\u3059\u3002Eric O. Aboagye\u3089\u306f\u3001\u65b0\u898f\u306a\u30b3\u30ea\u30f3\u7cfb\u3001 [18F]fluoro-[1,2-2H4]choline \u3092\u5408\u6210\u3057\u3001PET\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u30d7\u30ed\u30fc\u30d6\u3068\u3057\u3066\u306e\u8a55\u4fa1\u3092\u884c\u3063\u305f\u30023)\u4e0b\u8a18\u306b[18F]Fluorocholine\u3001[18F]fluoro-[1,2-2H2]choline\u3001[18F]fluoro-[1,2-2H4]choline\u306e\u5408\u6210\u6cd5\u3092\u793a\u3059\u3002
\n\"FT5\"
\n\u904e\u30de\u30f3\u30ac\u30f3\u9178\u30ab\u30ea\u3084\u30b3\u30ea\u30f3\u30aa\u30ad\u30b7\u30c0\u30fc\u30bc\u3092\u7528\u3044\u3066\u9178\u5316\u7684\u5b89\u5b9a\u6027\u3092\u8abf\u3079\u305f\u7d50\u679c\u3001[18F]fluoro-[1,2-2H4]choline\u306f[18F]Fluorocholine\u306b\u6bd4\u3057\u3066\u9ad8\u3044\u5b89\u5b9a\u6027\u3092\u793a\u3057\u305f\u3002\u305d\u3057\u3066\u3001\u3044\u305a\u308c\u306e\u30d5\u30c3\u7d20\u5316\u30b3\u30ea\u30f3\u3082\u307b\u3068\u3093\u3069\u306e\u81d3\u5668\u306b\u540c\u3058\u3088\u3046\u306b\u6442\u53d6\u3055\u308c\u305f\u3002\u307e\u305f\u3001\u816b\u760d\u6442\u53d6\u306b\u3064\u3044\u3066\u306e\u6642\u9593\u5909\u5316\u3092\u4e0b\u8a18\u306b\u793a\u3059\u3002\u3044\u305a\u308c\u3082[18F]fluoro-[1,2-2H4]choline\u304c\u4ed6\u306e\u30d5\u30c3\u7d20\u5316\u30b3\u30ea\u30f3\u3088\u308a\u3082\u9ad8\u3044\u5024\u3092\u793a\u3057\u300160\u5206\u5f8c\u306e\u5024\u306f\u975e\u5e38\u306b\u9ad8\u304f\u3001\u751f\u4f53\u5185\u3067\u306e\u8a66\u9a13\u306b\u4f9b\u3059\u308b\u306b\u5341\u5206\u4fa1\u5024\u304c\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u305f\u3002
\n\"FT6\"
\n4\u3001\u30c8\u30ec\u30fc\u30b5\u30fc\u306e\u65b0\u898f\u88fd\u9020\u65b9\u6cd5
\n18F\u6a19\u8b58\u5316\u5408\u7269\u306e\u5408\u6210\u306f\u3001\u901a\u5e38\u3001\u30b5\u30a4\u30af\u30ed\u30c8\u30ed\u30f3\u3092\u7528\u3044\u3066\u88fd\u9020\u3057\u305f\u77ed\u534a\u6e1b\u671f\u306e\u653e\u5c04\u6027\u540c\u4f4d\u5143\u7d2018F\u3092\u539f\u6599\u3068\u3057\u3066\u3001\u81ea\u52d5\u9060\u9694\u64cd\u4f5c\u304c\u53ef\u80fd\u306a\u5408\u6210\u88c5\u7f6e\u3092\u7528\u3044\u3066\u5408\u6210\u3055\u308c\u308b\u3002\u8fd1\u5e74\u300118F\u6a19\u8b58\u5316\u5408\u7269\u306e\u5408\u6210\u306b\u3001\u53cd\u5fdc\u64cd\u4f5c\u306b\u95a2\u3057\u3066\u5fae\u5c0f\u306a\u53cd\u5fdc\u6d41\u8def\u5185\u3067\u884c\u3046\u30de\u30a4\u30af\u30ed\u5316\u5b66\u30b7\u30b9\u30c6\u30e0\u3092\u9069\u7528\u3057\u305f\u65b9\u6cd5\u304c\u63d0\u6848\u3055\u308c\u3066\u3044\u308b\u30024)\u30015)
\n\u672c\u6cd5\u306f\u3001\u30de\u30a4\u30af\u30ed\u30c1\u30c3\u30d7\u3092\u7528\u3044\u305f\u65b9\u6cd5\u3067\u3042\u308a\u3001\u5185\u90e8\u306b\u6c17\u76f8\u306e\u6d41\u8def\u3092\u6709\u3059\u308b\u3068\u5171\u306b\u3001\u6c17\u76f8\u306e\u6d41\u8def\u306e\u5e95\u90e8\u306b\u6db2\u76f8\u3092\u6e9c\u3081\u308b\u30d7\u30fc\u30eb\u90e8\u3092\u6709\u3059\u308b\u30de\u30a4\u30af\u30ed\u30c1\u30c3\u30d7\u306b\u6db2\u76f8\u3068\u3057\u306618F\u30a4\u30aa\u30f3\u3092\u542b\u3093\u3060\u6eb6\u6db2\u3092\u5c0e\u5165\u3057\u3001\u30de\u30a4\u30af\u30ed\u30c1\u30c3\u30d7\u306e\u30d7\u30fc\u30eb\u90e8\u306b\u6bdb\u7ba1\u529b\u3092\u5229\u7528\u3057\u306618F\u30a4\u30aa\u30f3\u3092\u542b\u3093\u3060\u6eb6\u6db2\u3092\u5206\u6563\u3055\u305b\u308b\u5de5\u7a0b\u3068\u3001\u6c17\u76f8\u306e\u6d41\u8def\u306b\u7a92\u7d20\u30ac\u30b9\u306a\u3069\u3092\u6d41\u3057\u3066\u3001\u30d7\u30fc\u30eb\u90e8\u306b\u6e9c\u3081\u3089\u308c\u305f18F\u30a4\u30aa\u30f3\u3092\u542b\u3093\u3060\u6eb6\u6db2\u3092\u84b8\u767a\u4e7e\u56fa\u3055\u305b\u308b\u5de5\u7a0b\u3068\u3092\u5099\u3048\u308b\u65b9\u6cd5\u3067\u3042\u308b\u3002\u3053\u308c\u307e\u3067\u306f\u3001\u30de\u30a4\u30af\u30ed\u30c1\u30c3\u30d7\u5185\u3067\u84b8\u767a\u64cd\u4f5c\u3092\u52b9\u7387\u826f\u304f\u884c\u3046\u3053\u3068\u304c\u5b9f\u73fe\u3067\u304d\u3066\u3044\u306a\u3044\u3002\u3053\u3053\u3067\u306f\u3001\u84b8\u767a\u64cd\u4f5c\u3092\u542b\u3080\u591a\u6bb5\u968e\u5408\u6210\u30d7\u30ed\u30bb\u30b9\u3067\u3042\u308b18F\u6a19\u8b58\u5316\u5408\u7269\u306e\u5408\u6210\u3092\u3001\u52b9\u7387\u7684\u306a\u30de\u30a4\u30af\u30ed\u30c1\u30c3\u30d7\u4e0a\u306e\u64cd\u4f5c\u3068\u3057\u3066\u96c6\u7a4d\u5316\u3059\u308b\u3053\u3068\u3092\u8ab2\u984c\u3068\u3057\u3066\u3044\u308b\u3002
\n\u6a21\u5f0f\u56f3\u3092\u4e0b\u8a18\u306b\u793a\u3059\u3002\u30de\u30a4\u30af\u30ed\u30c1\u30c3\u30d731\u306f\u3001\u56fa\u76f8\u30d3\u30fc\u30ba\u5145\u586b\u90e832\u30682\u3064\u306e\u5fae\u7d30\u52a0\u5de5\u6e9d\u90e833\uff0c34\u3001\u30de\u30a4\u30af\u30ed\u30c1\u30e3\u30f3\u30cd\u30eb\u90e835\u3088\u308a\u69cb\u6210\u3055\u308c\u308b\u3002
\n\"FT7\"
\n\u5177\u4f53\u7684\u306b\u306f\u3001\u30b5\u30a4\u30af\u30ed\u30c8\u30ed\u30f3\u3067\u88fd\u9020\u3057\u305f18F\u30a4\u30aa\u30f3\u542b\u6709\u9178\u7d2018O\u6fc3\u7e2e\u6c342mL\u3092\u5c0e\u5165\u8def37\u3088\u308a\u56fa\u76f8\u30d3\u30fc\u30ba\u5145\u586b\u90e832\u306b\u6d41\u3057\u3001\u56fa\u76f8\u30d3\u30fc\u30ba\u5145\u586b\u90e832\u306b\u5145\u586b\u3055\u308c\u305f\u9670\u30a4\u30aa\u30f3\u4ea4\u63db\u6a39\u8102\u306b18F\u30a4\u30aa\u30f3\u3092\u30c8\u30e9\u30c3\u30d7\u3055\u305b\u305f\u3002\u305d\u306e\u5f8c\u3001\u56fa\u76f8\u30d3\u30fc\u30ba\u5145\u586b\u90e832\u306b\u5c0e\u5165\u8def37\u3088\u308a0.8mg\u70ad\u9178\u30ab\u30ea\u30a6\u30e0\u53ca\u30734.8mg\u76f8\u9593\u79fb\u52d5\u89e6\u5a92\u30af\u30ea\u30d7\u30bf\u30f3\u30c9\u3092\u542b\u3080\u30a2\u30bb\u30c8\u30cb\u30c8\u30ea\u30eb\uff0f\u6c34(9:1)\u6eb6\u6db250\u03bcL\u3092\u6d41\u3057\u300118F\u30a4\u30aa\u30f3\u3092\u6eb6\u96e2\u3055\u305b\u3001\u6392\u51fa\u8def36\u304b\u3089\u5c0e\u5165\u8def38\u3092\u901a\u3057\u3066\u5fae\u7d30\u52a0\u5de5\u6e9d\u90e833\u306b\u4f9b\u7d66\u3057\u305f\u3002\u5fae\u7d30\u52a0\u5de5\u6e9d\u90e833\u3092120\u00baC\u306b\u52a0\u71b1\u3057\u3001\u5c0e\u5165\u8def38\u3088\u308a\u7a92\u7d20\u30ac\u30b9\u3092\u6d41\u3057\u306a\u304c\u3089\u84b8\u767a\u4e7e\u56fa\u3092\u884c\u3063\u305f\u3002\u84b8\u767a\u4e7e\u56fa\u7d42\u4e86\u5f8c\u3001\u53cd\u5fdc\u524d\u99c6\u4f53\u3067\u3042\u308b2-\u30d6\u30ed\u30e2\u30a8\u30c1\u30eb\u30c8\u30ea\u30d5\u30ec\u30fc\u30c83\u03bcL\u3092\u542b\u3080o-\u30b8\u30af\u30ed\u30ed\u30d9\u30f3\u30bc\u30f3\u6eb6\u6db250\u03bcL\u3092\u5c0e\u5165\u8def38\u3088\u308a\u5fae\u7d30\u52a0\u5de5\u6e9d\u90e833\u306b\u4f9b\u7d66\u3057\u3001100\u00baC\u3067\u6a19\u8b58\u53cd\u5fdc\u3092\u884c\u3063\u305f\u3002\u5c0e\u5165\u8def38\u3088\u308a\u7a92\u7d20\u30ac\u30b9\u309210mL\/min\u3067\u6d41\u3057\u306a\u304c\u3089\u5408\u6210\u3055\u308c\u305f18F\u6a19\u8b58\u30d5\u30eb\u30aa\u30ed\u30a8\u30c1\u30eb\u30d6\u30ed\u30df\u30c9\u3092\u84b8\u7559\u3057\u305f\u3002\u84b8\u7559\u3057\u305f18F\u6a19\u8b58\u30d5\u30eb\u30aa\u30ed\u30a8\u30c1\u30eb\u30d6\u30ed\u30df\u30c9\u306f\u3001\u6392\u51fa\u8def39\u304b\u3089\u5c0e\u5165\u8def42\u3092\u901a\u308a\u3001\u30de\u30a4\u30af\u30ed\u30c1\u30e3\u30f3\u30cd\u30eb\u90e835\u53ca\u3073\u5fae\u7d30\u52a0\u5de5\u6e9d\u90e834\u306b\u4f9b\u7d66\u3057\u3001\u524d\u99c6\u4f53\u306eL-\u30c1\u30ed\u30b7\u30f3\u53ca\u3073\u6c34\u9178\u5316\u30ca\u30c8\u30ea\u30a6\u30e0\u3092\u542b\u3080DMSO(\u30b8\u30e1\u30c1\u30eb\u30b9\u30eb\u30db\u30ad\u30b7\u30c9)\u6eb6\u6db2\u3068\u63a5\u89e6\u3055\u305b\u3001\u6c17\u6db2\u53cd\u5fdc\u3092\u884c\u3063\u305f\u3002\u30de\u30a4\u30af\u30ed\u30c1\u30e3\u30f3\u30cd\u30eb\u90e835\u53ca\u3073\u5fae\u7d30\u52a0\u5de5\u6e9d\u90e834\u3092200\u00baC\u306b\u52a0\u71b1\u3057\u3001\u5c0e\u5165\u8def42\u3088\u308a\u7a92\u7d20\u30ac\u30b9\u3092\u6d41\u3057\u306a\u304c\u3089\u6eb6\u5a92\u3092\u7559\u53bb\u3057\u305f\u30020.15mol\/L\u308a\u3093\u9178\u7de9\u885d\u6db2\u3092\u5c0e\u5165\u8def42\u3088\u308a\u30de\u30a4\u30af\u30ed\u30c1\u30e3\u30f3\u30cd\u30eb\u90e835\u53ca\u3073\u5fae\u7d30\u52a0\u5de5\u6e9d\u90e834\u306b\u4f9b\u7d66\u3057\u3001\u6392\u51fa\u8def41\u3088\u308a18F\u6a19\u8b58FET(\u30d5\u30eb\u30aa\u30ed\u30a8\u30c1\u30eb\u30c1\u30ed\u30b7\u30f3)\u3092\u5f97\u305f\u3002<\/p>\n

5\u3001\u304a\u308f\u308a\u306b
\n18F\u6a19\u8b58\u5316\u5408\u7269\u306f\u30a2\u30df\u30ce\u9178\u3001\u30b3\u30ea\u30f3\u3001\u30b0\u30eb\u30b3\u30fc\u30b9\u306a\u3069\u3068\u3057\u3066\u3001\u764c\u8a3a\u65ad\u3084\u8133\u6a5f\u80fd\u8a3a\u65ad\u306b\u6709\u7528\u306a\u81e8\u5e8aPET\u8a3a\u65ad\u306b\u4eca\u3084\u6b20\u304b\u305b\u306a\u3044\u3082\u306e\u3067\u3042\u308a\u3001\u4eca\u5f8c\u76ca\u3005\u305d\u306e\u91cd\u8981\u6027\u3092\u5897\u3057\u3066\u3044\u304f\u3068\u8003\u3048\u3066\u3044\u308b\u300218F\u306e\u7d20\u6027\u306e\u826f\u3044\u30c8\u30ec\u30fc\u30b5\u30fc\u3068\u3057\u3066\u306e\u7279\u5fb4\u3068F\u539f\u5b50\u306e\u512a\u308c\u305f\u8102\u6eb6\u6027\u306b\u3088\u308b\u751f\u4f53\u5185\u3078\u306e\u52b9\u7387\u7684\u306a\u53d6\u308a\u8fbc\u307f\u304c\u76f8\u307e\u3063\u305f\u7d50\u679c\u3067\u3042\u308a\u3001\u3055\u3089\u306b\u30de\u30a4\u30af\u30ed\u30c1\u30c3\u30d7\u6cd5\u306a\u3069\u306e\u6709\u52b9\u306a\u5408\u6210\u6cd5\u306e\u958b\u767a\u3082\u91cd\u8981\u3067\u3042\u308b\u3002<\/p>\n

\u6587\u732e\u30fb\u7279\u8a31
\n1) Hank F. Kung et al Nuclear Medicine and Biology 38(2011) 53-62
\n2) Johannes Ermert et al Organic & Biomolecular Chemistry 9(2011)\u3000765-769
\n3) Eric O. Aboagye et al Nuclear Medicine and Biology 38(2011) 39-51
\n4) JFE\u30a8\u30f3\u30b8\u30cb\u30e4\u30ea\u30f3\u30b0\u3000\u7279\u958b2010-235462
\n5) JFE\u30a8\u30f3\u30b8\u30cb\u30e4\u30ea\u30f3\u30b0\u3000\u7279\u958b2010-260799<\/p>\n","protected":false},"excerpt":{"rendered":"

\u6700\u65b0\u30d5\u30c3\u7d20\u95a2\u9023\u30c8\u30d4\u30c3\u30af\u30b9\u300d\u306f\u30c0\u30a4\u30ad\u30f3\u5de5\u696d\u682a\u5f0f\u4f1a\u793e\u30d5\u30a1\u30a4\u30f3\u30b1\u30df\u30ab\u30eb\u90e8\u306e\u3054\u597d\u610f\u306b\u3088\u308a\u3001\u30c0\u30a4\u30ad\u30f3\u5de5\u696d\u30db\u30fc\u30e0\u30da\u30fc\u30b8\u306eWEB\u30de\u30ac\u30b8\u30f3\u306b\u63b2\u8f09\u3055\u308c\u305f\u5185\u5bb9\u3092\u7d39\u4ecb\u3057\u3066\u3044\u307e\u3059\u3002\u3054\u611b\u9867\u306e\u307b\u3069\u3088\u308d\u3057\u304f\u304a\u9858\u3044\u3044\u305f\u3057\u307e\u3059\u3002\u5c1a\u3001WEB\u30de\u30ac\u30b8\u30f3\u306eURL … \u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-311","post","type-post","status-publish","format-standard","hentry","category-1"],"_links":{"self":[{"href":"https:\/\/ft-net.co.jp\/topic\/index.php?rest_route=\/wp\/v2\/posts\/311","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ft-net.co.jp\/topic\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ft-net.co.jp\/topic\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ft-net.co.jp\/topic\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ft-net.co.jp\/topic\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=311"}],"version-history":[{"count":2,"href":"https:\/\/ft-net.co.jp\/topic\/index.php?rest_route=\/wp\/v2\/posts\/311\/revisions"}],"predecessor-version":[{"id":590,"href":"https:\/\/ft-net.co.jp\/topic\/index.php?rest_route=\/wp\/v2\/posts\/311\/revisions\/590"}],"wp:attachment":[{"href":"https:\/\/ft-net.co.jp\/topic\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=311"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ft-net.co.jp\/topic\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=311"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ft-net.co.jp\/topic\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=311"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}